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1.
Mymensingh Med J ; 32(2): 510-519, 2023 Apr.
Article in English | MEDLINE | ID: mdl-37002765

ABSTRACT

The goal of this study was to analyze the efficacy of the Ommaya reservoir within all the different types of hydrocephalus in pediatric patients. At the same time, it's safe for repeated aspirations or long-term retention of the reservoir in the body. This retrospective, cross-sectional study was performed from January 2019 to December 2021, 33 consecutive cases of reservoir implantation were taken into the study irrespective of the etiology of hydrocephalus in the Neurosurgery Department of Bangladesh Medical College Hospital, Dhaka, Bangladesh. These were mostly placed along with endoscopic third ventriculostomy and some were placed as an intermediary procedure to combat shunt complications in emaciated infants. Cerebrospinal fluid (CSF) aspiration was done in case of failed endoscopic third ventriculostomy and the frequency of aspiration depended upon the production of cerebrospinal fluid. Acetazolamide was routinely administered in each patient to reduce the frequency of aspiration. Most of the patients required ventriculo-peritoneal (VP) shunt while they had sufficient body weight and few required no surgery. The average age at presentation was 76.88 days. All the neonates and infants had less weight in terms of their age. 42.4% of babies needed aspiration 2 times per week. Among all cases, 9.1% developed reservoir complications. Complications were not related to the number and volume of aspiration or duration of the reservoir in the body. Two (2) patients died after one year of reservoir implantation due to unknown etiology. Out of the 31 survivors, 3 patients did not need any further aspiration and 19 patients needed a ventriculo-peritoneal shunt, but the reservoir was kept in situ for a future emergency. The rest of them is waiting for a definitive shunt procedure. Other findings include low socioeconomic group was more prone to low birth weight and they carried the burden of congenital hydrocephalus and meningomyelocele. Most affected babies had their prenatal period in arsenic-affected areas in Bangladesh. Overall folic acid supplementation was started after the formation of the neural tube irrespective of socioeconomic status. Ommaya reservoir placement along with endoscopic third ventriculostomy plays a vital role in delaying shunt in endoscopic third ventriculostomy failure. It is a 'time buying' procedure until the baby has sufficient weight for successful shunt surgery. It has been found very effective intermediary intervention for managing shunt infection and it also helps revive a channel in shunt obstruction.


Subject(s)
Cerebral Hemorrhage , Hydrocephalus , Infant, Newborn , Infant , Humans , Child , Retrospective Studies , Bangladesh/epidemiology , Cross-Sectional Studies , Hydrocephalus/surgery , Hydrocephalus/complications , Treatment Outcome
2.
Environ Sci Pollut Res Int ; 29(25): 37633-37643, 2022 May.
Article in English | MEDLINE | ID: mdl-35066842

ABSTRACT

Bismuth molybdate (Bi2MoO6) nanostructures has attracted many researches as an advanced photocalysts for the organic contaminants. In this paper, bismuth molybdate Bi2MoO6 nanoparticles were synthesized using a simple hydrothermal method at varied pH (2, 4, 6, 8, and 10) for 15 h at 180 °C. The results reveal the variation pH precursor solutions have a significant impact on the morphology, phase formations, and photocatalytic activity of samples. The synthesized samples at low pH level were characterized by FESEM analysis revealing Bi2MoO6 nanoplates have formed while gradually convert to Bi2MoO6 spherical nanoparticle at high PH level as shown in energy dispersive X-ray spectroscopy (DES) peaks. The X-ray diffraction patterns reveal characteristic peaks corresponding to mixed phases of Bi2MoO6 and cubic Bi4MoO9 at high pH value. The optical absorption study exhibit Bi2MoO6 nanoplates absorbed visible light with blue shift when compared to the cubic Bi4MoO9 structures. Moreover, the photocatalytic activity results revealed that nanoplates in pH = 4 sample has excellent photocatalytic activity for degradation of rhodamine (RhB), methylene orange (MO), and phenol under visible-light irradiation (λ > 400 nm) as well as exhibit the photodegradation 90% of phenol within 300 min.


Subject(s)
Environmental Pollutants , Nanostructures , Bismuth/chemistry , Catalysis , Hydrogen-Ion Concentration , Molybdenum , Phenols
3.
Malays Orthop J ; 15(2): 18-25, 2021 Jul.
Article in English | MEDLINE | ID: mdl-34429818

ABSTRACT

INTRODUCTION: Fractures around the hip in the geriatric population not only lead to functional but also psychological impairment. Psychiatric disturbances can be associated with poor participation in rehabilitation, increased risk of falling again, and higher rates of mortality. The present study was undertaken to assess the association between the psychological status and functional outcome of surgically managed elderly Indian patients who had sustained fractures around the hip. MATERIAL AND METHODS: The present study was a hospital based prospective, single centre study. One hundred and two geriatric patients who had sustained hip fracture and had been managed surgically, having no cognitive dysfunction, living independently, having unhindered walking capability before the fracture, were included in the study. They were called for follow-up at 3rd, 6th, and 12th month after the hip surgery. Psychological assessment was done by the Hospital Anxiety and Depression Scale (HADS) and functional outcome by using the Harris hip score (HHS). RESULTS: Our study did not show association between psychological status and functional outcome except in one sub-group. Significant correlation was observed between the psychological status and functional outcome in most of the patients in the extra-capsular group. We have identified improvement in the depression, anxiety and functional scores during the follow-up. CONCLUSION: We conclude that psychiatric disturbances in a geriatric patient after undergoing a surgery for hip fracture may lead to poor recovery. We recommend that all such geriatric patients should undergo a psychological assessment and proper therapy should be instituted to achieve good functional recovery.

4.
Cureus ; 13(5): e15017, 2021 May 13.
Article in English | MEDLINE | ID: mdl-34007778

ABSTRACT

Toxic epidermal necrolysis (TEN) is a rare, but potentially fatal dermatological emergency most commonly caused by medication exposure. It is characterized by skin desquamation affecting over 30% of the body, and it remains a fatal condition with a high mortality rate. Nivolumab, an immune checkpoint inhibitor used in the treatment of various types of malignancies, has been linked to TEN. Nivolumab-induced TEN is a rare phenomenon with a low incidence rate in patients treated with a single-agent immune checkpoint inhibitor, but it has a high mortality rate that exceeds non-nivolumab-induced TEN. Nivolumab-induced TEN can present with many potential complications such as hemodynamic instability from excessive fluid loss, sepsis from bacterial superinfection, and disseminated intravascular coagulation. Due to its high mortality rate, prompt recognition of the condition, immediate withdrawal of the offending drug(s), vigorous skin care, multispecialty collaboration, and close monitoring of complications is needed. We present a case of nivolumab-induced TEN in an elderly male with a history of hepatocellular carcinoma who presented with acute-onset skin desquamation after nivolumab initiation.

5.
Heliyon ; 7(2): e06025, 2021 Feb.
Article in English | MEDLINE | ID: mdl-33659722

ABSTRACT

The movement of positive people Coronavirus Disease that was discovered in 2019 (Covid-19), written 2019-nCoV, from one location to another has a great opportunity to transmit the virus to more people. High-risk locations for transmission of the virus are public transportations, one of which is the train, because many people take turns in or together inside. One of the policies of the government is physical distancing, then followed by large-scale social restrictions. The keys to the policy are distance and movement. The most famous transportation used for the movement of people among provinces on Java is train. Here a Generalized Space Time Autoregressive (GSTAR) model is applied to forecast infected case of 2019-nCoV for 6 provinces in Java. The specialty of this model is the weight matrix as a tool to see spatial dependence. Here, the modified Inverse Distance Weight matrix is proposed as a combination of the population ratio factor with the average distance of an inter-provincial train on the island of Java. The GSTAR model (1; 1) can capture the pattern of daily cases increase in 2019-nCoV, evidenced by representative results, especially in East Java, where the increase in cases is strongly influenced by other provinces on the island of Java. Based on the Mean Squares of Residuals, it is obtained that the modified matrix gives better result in both estimating (in-sample) and forecasting (out-sample) compare with the ordinary matrix.

6.
Article in English | WPRIM (Western Pacific) | ID: wpr-920837

ABSTRACT

@#Introduction: Fractures around the hip in the geriatric population not only lead to functional but also psychological impairment. Psychiatric disturbances can be associated with poor participation in rehabilitation, increased risk of falling again, and higher rates of mortality. The present study was undertaken to assess the association between the psychological status and functional outcome of surgically managed elderly Indian patients who had sustained fractures around the hip. Materials and methods: The present study was a hospital based prospective, single centre study. One hundred and two geriatric patients who had sustained hip fracture and had been managed surgically, having no cognitive dysfunction, living independently, having unhindered walking capability before the fracture, were included in the study. They were called for follow-up at 3rd, 6th, and 12th month after the hip surgery. Psychological assessment was done by the Hospital Anxiety and Depression Scale (HADS) and functional outcome by using the Harris hip score (HHS). Results: Our study did not show association between psychological status and functional outcome except in one sub-group. Significant correlation was observed between the psychological status and functional outcome in most of the patients in the extra-capsular group. We have identified improvement in the depression, anxiety and functional scores during the follow-up. Conclusion: We conclude that psychiatric disturbances in a geriatric patient after undergoing a surgery for hip fracture may lead to poor recovery. We recommend that all such geriatric patients should undergo a psychological assessment and proper therapy should be instituted to achieve good functional recovery

7.
Sultan Qaboos Univ Med J ; 20(1): e29-e36, 2020 Feb.
Article in English | MEDLINE | ID: mdl-32190367

ABSTRACT

OBJECTIVES: Stigma and discrimination undermine the quality of life of people with HIV and their access to health services. This study aimed to assess HIV-related knowledge, attitudes and practices among healthcare workers (HCWs) in Oman. METHODS: This cross-sectional study took place between July and November 2016. A questionnaire was distributed to 1,400 government HCWs to determine HIV-related knowledge, attitudes and practices. RESULTS: A total of 1,281 HCWs participated (response rate = 92%). Routine tasks, such as dressing wounds, drawing blood and touching clothes, were a cause of concern for 24-52% of HCWs. Only 69% correctly answered questions regarding the transmission of HIV via eating/drinking and mosquito bites. Compared to other HCWs, doctors had significantly higher knowledge (mean = 0.46, 95% confidence interval [CI]: 0.19 to 0.73; P <0.001), attitude (mean = 0.77, 95% CI: 0.31 to 1.24; P = 0.001) and practice (mean = 2.07, 95% CI: 1.59 to 2.55; P <0.001) scores. Expatriates also scored significantly higher in knowledge (mean = 1.08, 95% CI: 0.93 to 1.23; P <0.001), attitude (mean = 1.23, 95% CI: 0.98 to 1.48; P <0.001) and practice (mean = 1.08, 95% CI: 0.82 to 1.34; P <0.001) compared to Omani nationals. Finally, those with >15 years' work experience scored significantly higher on knowledge (mean = -0.60, 95% CI: -1.12 to -0.08; P = 0.025) and attitude (mean = -0.99, 95% CI: -1.87 to -0.10; P = 0.029) compared to those with less experience. CONCLUSION: The high rate of HIV-related stigma among HCWs in Oman should be rectified in order to achieve the 90-90-90 target set by the Joint United Nations Programme on HIV/AIDS.


Subject(s)
HIV Infections/psychology , Health Knowledge, Attitudes, Practice , Health Personnel/psychology , Social Discrimination/psychology , Social Stigma , Adult , Attitude of Health Personnel , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Oman , Surveys and Questionnaires
8.
Int Nurs Rev ; 67(2): 231-238, 2020 Jun.
Article in English | MEDLINE | ID: mdl-31713860

ABSTRACT

OBJECTIVE: The objective is to assess the reasoning by families in deciding between a home vs. facility delivery and vaginal vs. caesarean. STUDY DESIGN: The authors selected a convenience sample of 16 villages in Sathkira district in southwest Bangladesh. Evidence was drawn from detailed in-home post-delivery interviews with all mothers in these villages who delivered in 2015 or 2016. METHODS: Local family health workers and paramedics used a structured questionnaire that enabled gathering of relevant quantitative and qualitative evidence. Mothers' reasons for selection of delivery location and type were categorized, and regression analysis was conducted to assess significance of variables that proxy supply and demand factors. RESULTS: Among 492 completed interviews, 48% were home deliveries, 52% facility deliveries; two-thirds of facility deliveries in private clinics. Overall, sample caesarean rate is 39%, public hospital rate 53%, private clinic rate 86%. Over half of reasons for home delivery refer to pregnancy without complication or access to trusted birth attendant. Over half of reasons for facility delivery refer to medical complications allegedly precluding home delivery, or requiring home-to-facility transfer during labour for reasons not clear to the mother. The decision depends on both 'demand' factors originating with the family (proxied by family income, birth order and education levels) and 'supply' factors originating with obstetric care providers (proxied by number of antenatal visits and variation of caesarean rate by village). In a regression controlling for both demand and supply variables, the above proxy variables are all significant. IMPLICATIONS FOR NURSING AND HEALTH POLICY: Bangladesh has inadequate nursing support for vaginal delivery in either home or facility. Hence, physicians frequently recommend that women deliver in a facility (usually a physician's clinic). Physicians are reluctant to hire adequate nurses to attend vaginal deliveries. Hence, families with some discretionary income are increasingly opting for a caesarean over vaginal delivery. Facility deliveries reduce incidence of obstructed labour fistula, but probably contribute to rising incidence of iatrogenic fistula. Reducing caesarean rates requires a large increase in numbers of nurses and midwives, and acceptance by physicians of a broad scope of practice for nurses/midwives in vaginal deliveries.


Subject(s)
Cesarean Section/psychology , Cesarean Section/statistics & numerical data , Delivery, Obstetric/psychology , Delivery, Obstetric/statistics & numerical data , Family/psychology , Home Childbirth/psychology , Patient Preference/psychology , Patient Preference/statistics & numerical data , Adult , Female , Home Childbirth/statistics & numerical data , Humans , Male , Pregnancy , Qualitative Research
9.
J Environ Manage ; 204(Pt 1): 75-81, 2017 Dec 15.
Article in English | MEDLINE | ID: mdl-28865309

ABSTRACT

The main problem of landfill leachate is its diverse composition comprising many persistent organic pollutants which must be removed before being discharge into the environment. This study investigated the treatment of raw landfill leachate using electrocoagulation process. An electrocoagulation system was designed with iron as both the anode and cathode. The effects of inter-electrode distance, initial pH and electrolyte concentration on colour and COD removals were investigated. All these factors were found to have significant effects on the colour removal. On the other hand, electrolyte concentration was the most significant parameter affecting the COD removal. Numerical optimization was also conducted to obtain the optimum process performance. Under optimum conditions (initial pH: 7.73, inter-electrode distance: 1.16 cm, and electrolyte concentration (NaCl): 2.00 g/L), the process could remove up to 82.7% colour and 45.1% COD. The process can be applied as a pre-treatment for raw leachates before applying other appropriate treatment technologies.


Subject(s)
Electrocoagulation/methods , Iron/chemistry , Water Pollutants, Chemical/chemistry , Electrodes , Hydrogen-Ion Concentration
10.
World J Surg ; 41(7): 1743-1751, 2017 07.
Article in English | MEDLINE | ID: mdl-28275833

ABSTRACT

OBJECTIVE: Evaluate the capacity of government-run hospitals in Bangladesh to provide emergency and essential surgical, obstetric and anaesthetic services. METHODS: Cross-sectional survey of 240 Bangladeshi Government healthcare facilities using the World Health Organisation Situational Analysis Tool to Assess Emergency and Essential Surgical Care (SAT). This tool evaluates the ability of a healthcare facility to provide basic surgical, obstetric and anaesthetic care based on 108 queries that detail the infrastructure and population demographics, human resources, surgical interventions and reason for referral, and available surgical equipment and supplies. For this survey, the Bangladeshi Ministry of Health sent the SAT to sub-district, district/general and teaching hospitals throughout the country in April 2013. RESULTS: Responses were received from 240 healthcare facilities (49.5% response rate): 218 sub-district and 22 district/general hospitals. At the sub-district level, caesarean section was offered by 55% of facilities, laparotomy by 7% and open fracture repair by 8%. At the district/general hospital level, 95% offered caesarean section, 86% offered laparotomy and 77% offered open fracture treatment. Availability of anaesthesia services, general equipment and supplies reflected this trend, where district/general hospitals were better equipped than sub-district hospitals, though equipment and infrastructure shortages persist. CONCLUSION: There has been overall impressive progress by the Bangladeshi Government in providing essential surgical services. Areas for improvement remain across all key areas, including infrastructure, human resources, surgical interventions offered and available equipment. Investment in surgical services offers a cost-effective opportunity to continue to improve the health of the Bangladeshi population and move the country towards universal healthcare coverage.


Subject(s)
Anesthesiology , Emergency Medical Services , Health Facilities , Health Services Accessibility , Obstetrics , Bangladesh , Cesarean Section , Cross-Sectional Studies , Female , Government , Humans , Pregnancy
11.
Skin Pharmacol Physiol ; 29(2): 76-82, 2016.
Article in English | MEDLINE | ID: mdl-27035720

ABSTRACT

BACKGROUND: The vitamin D endocrine system, besides multiple other functions, regulates aging in many tissues, including the skin. It protects the skin against the hazardous effects of many skin age-inducing agents, including ultraviolet radiation. Thus, in the present study we aimed to investigate the relationship between facial skin aging and 25-hydroxyvitamin D [25(OH)D] serum levels in healthy Egyptian adults. METHODS: Sixty-one healthy adult subjects were included. Photodamage scores (erythema/telangiectasias, lentigines, hyperpigmentation and coarse wrinkling) were assessed and graded. Serum vitamin D was measured using enzyme immunoassay and subjects were classified as sufficient, insufficient or deficient according to the vitamin level. RESULTS: The mean 25(OH)D serum level was 43.90 nmol/l. A high prevalence of vitamin D deficiency was detected in the studied subjects regardless of their age or gender. Also, vitamin D levels were not correlated with photodamage scores and were not affected by the Fitzpatrick skin phototype, duration of sun exposure per day or the use of sunscreens (p > 0.05 for all). CONCLUSIONS: Aging is a complex process that is influenced by many genetic and environmental factors. Facial aging is not correlated with serum vitamin D level, and clinical trials using oral or topical vitamin D to combat aging are better predictors of its effects rather than in vivo studies.


Subject(s)
Skin Aging/pathology , Skin Aging/physiology , Vitamin D Deficiency/blood , Vitamin D Deficiency/diagnosis , Vitamin D/analogs & derivatives , Adult , Aged , Egypt/epidemiology , Female , Humans , Male , Middle Aged , Vitamin D/blood , Vitamin D Deficiency/epidemiology , Young Adult
12.
J Popul Ther Clin Pharmacol ; 23(1): e26-36, 2016.
Article in English | MEDLINE | ID: mdl-26950049

ABSTRACT

BACKGROUND: Thiopurines (Azathioprine (AZA) and 6-Mercaptopurine (6-MP) are considered a well-established therapy for patients with Inflammatory Bowel Disease (IBD) including ulcerative colitis (UC) and Crohn's Disease (CD). However, nearly 20% of patients discontinue thiopurines due to adverse events. Functional polymorphisms of several enzymes involved in the metabolism of thiopurines have been linked with toxicity. The clinical value of variant carriers such as TPMT, ITPA and GSTs in predicting toxicity and adverse events for IBD patients treated with thiopurines remains to be clarified. OBJECTIVES: To determine if variation in TPMT, ITPA and GST genotypes can predict adverse effects such as neutropenia, pancreatitis, liver enzyme elevation, as well as clinical response for patients with IBD treated with thiopurines. METHODS: Patients known to have IBD and treated with AZA or 6MP were enrolled. Adverse effects were calculated and their correlation with TPMT, ITPA and GST genotypes was evaluated. Further, the correlation between clinical response and TPMT, ITPA and GST genotypes were assessed. RESULTS: A total of 53 patients were enrolled. 16/53 patients (28.6%) responded to AZA therapy. 17 patients experienced adverse events with 10 having to discontinue treatment. Three patients (5.4%) developed severe myelosuppression (WBC< 2.0 or neutrophils <1.0). Loss of function TPMT genotype was associated with adverse events (OR 3.64, 95% CI 0.55 - 24.23, p=0.0313). ITPA and GST polymorphisms were not associated with toxicity. GSTM1 deletion was associated with poor clinical response to therapy (OR 3.75, 95% CI 0.940 - 14.97, p=0.1028), however, neither TPMT*3A nor ITPA polymorphisms were associated with clinical response. CONCLUSION: In addition to TPMT for adverse events, genotyping for GSTM1 appears to predict clinical response in IBD patients treated with thiopurines.


Subject(s)
Azathioprine/adverse effects , Genetic Markers/genetics , Inflammatory Bowel Diseases/drug therapy , Inflammatory Bowel Diseases/genetics , Adult , Aged , Aged, 80 and over , Diarrhea/chemically induced , Female , Follow-Up Studies , Glutathione Transferase/genetics , Humans , Immunosuppressive Agents/adverse effects , Inflammatory Bowel Diseases/diagnosis , Male , Middle Aged , Nausea/chemically induced , Predictive Value of Tests , Prospective Studies , Treatment Outcome , Young Adult
13.
J Nanosci Nanotechnol ; 15(11): 9275-80, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26726682

ABSTRACT

Non-hydrogenated amorphous Silicon-Germanium (a-SiGe) thin films were deposited at two different base pressures by RF magnetron co-sputtering. Moreover, an ex-situ thermal annealing was carried out to investigate the material properties to be suitable as the bottom cell of multi-junction solar cells. Compositional study of the films using EDX showed Ge-rich thin films with 75 atomic% of Ge. XRD reflection study implied that all samples were entirely amorphous in nature. However, a significant improvement of morphology possibly due to low base pressure was observed while thermal annealing caused peening and reduction of surface inhomogeneity in both as-sputtered films. UV-VIS-IR analysis confirmed the FESEM results. The highest transmittance was observed in the as-deposited sample grown at 4 x 10(-5) Torr, which however reduced after thermal annealing. Tauc's model was implied for band gap determination and band gap energy as low as 1.07 eV was found in the annealed sample grown at lower base pressure (4 x 10(-6) Torr). Electrical properties of films were investigated by Hall effect measurement system and results found the reduction of resistivity with the same trend of optical band gap energy.

14.
J Clin Diagn Res ; 8(5): LD01-2, 2014 May.
Article in English | MEDLINE | ID: mdl-24995199

ABSTRACT

Osteochondroma or osteocartolaginous exostosis is by far the most common benign bone tumour, which accounts for 35% to 50% of benign bone neoplasms and 10% to 15% of all primary bone tumours. Osteochondroma represents a developmental enchondromatous hyperplasia which leads to formation of cartilage capped bony protrusions on bony surfaces. We present a case report of a 14-year- old female, who presented to us with a hard, gradually progressing, large painless swelling, over the left side of her neck. Swelling was nontender, extending from dorsal to ventral aspect, measuring 6 x 8 cm. Therefore, we are interested in introducing our case to medical fraternity, in which a giant lower cervical spine osteochondroma was seen in an adolescent female patient.

15.
J Clin Diagn Res ; 7(8): 1666-8, 2013 Aug.
Article in English | MEDLINE | ID: mdl-24086869

ABSTRACT

INTRODUCTION: Intercondylar (T-Condylar) fractures of the humerus are very rare in children. The usual mechanism of the injury which is involved is a fall on a flexed elbow. The treatment options vary, depending upon the degree of the displacement and the amount of comminution and; they may range from a simple application of traction to open reduction and internal fixation with plates and screws. Open reduction is associated with significant post-operative stiffness of the elbow and subsequent less than satisfactory functional results. In this publication, we are presenting our experience of treating seven adolescent T-Condylar fractures of the distal humerus with closed reductions and internal fixations with the percutaneus Kirchner ('K') wire. METHOD: Seven patients (M:F-6:1) with an average age of 14(range 12-16) years were treated by closed reduction and internal fixation with a 2.0 mm 'K' wire fixation under an image intensifier. Following the surgery, all the elbows were immobilised in plaster of Paris (POP) splints for three weeks. At three weeks after the surgery, the pop splints were removed and gentle elbow exercises were started. Five weeks after the surgery, the 'K' wires were removed, based on the radiological evidence of a bridging callus formation. RESULTS: Six patients (85%) out of seven showed satisfactory functional results on the Mayo Elbow Performance Score (MEPS), with a good range of motion at the elbow joint. Three (42%) patients had mild elbow stiffness, which resolved on subsequent treatment, while one (14%) had a mild pin tract infection, who was managed conservatively. There was one patient (14%) who was lost to follow-up, who ultimately had a painful and a stiff elbow. The remaining six patients were able to return to the premorbid sate. CONCLUSION: We recommend closed reduction and percutaneous 'K' wire fixation for adolescent T- Condylar fractures of the humerus as an easy and inexpensive procedure with satisfactory functional results.

16.
J R Coll Physicians Edinb ; 43(2): 103-7, 2013.
Article in English | MEDLINE | ID: mdl-23734349

ABSTRACT

BACKGROUND: Clostridum difficile (C. difficile) infection is increasingly seen among hospitalised patients with type 2 diabetes mellitus but its rate and associated risk factors are not known. We aimed to determine the rate and characteristics of hospital-acquired C. difficile infection in subjects with type 2 diabetes mellitus admitted into acute medical wards. METHODS: Our prospective cross-sectional study involved 159 patients with established type 2 diabetes mellitus admitted into acute medical wards who developed a hospital-acquired C. difficile infection. Stools were tested for C. difficile toxins using a toxin A/B kit and a toxin A kit. Clinical features, laboratory findings, types of antibiotics, and use of a proton pump inhibitor were examined for their association with the infection. RESULTS: Thirteen subjects were positive for toxin A and one for toxin B. Using univariable analysis, we found that patients with type 2 diabetes mellitus and hospital acquired C. difficile infection were younger (mean 53.8 years, p=0.02), had diarrhoea and abdominal pain (p=0.001) but no fever. Sepsis (p=0.02) and use of a proton pump inhibitor (p=0.01) were more commonly implicated as the cause of the infection. Of the various types of antibiotics prescribed, carbapenem (28.6% vs 4.1%, p=0.01) and metronidazole (42.9% vs 19.3%, p=0.04) were significantly associated with hospital acquired C. difficile infection. CONCLUSIONS: Patients with type 2 diabetes mellitus admitted into acute medical wards and who developed hospital-acquired C. difficile infection have distinct characteristics.


Subject(s)
Anti-Bacterial Agents/adverse effects , Clostridioides difficile , Clostridium Infections/chemically induced , Cross Infection/etiology , Diabetes Mellitus, Type 2/complications , Proton Pump Inhibitors/adverse effects , Sepsis/complications , Abdominal Pain/chemically induced , Age Factors , Aged , Bacterial Proteins/analysis , Bacterial Toxins/analysis , Clostridium Infections/epidemiology , Cross Infection/epidemiology , Cross-Sectional Studies , Diabetes Mellitus, Type 2/drug therapy , Diarrhea/chemically induced , Enterotoxins/analysis , Female , Hospitalization , Humans , Male , Metronidazole/adverse effects , Middle Aged , Prospective Studies
17.
Bangladesh Med Res Counc Bull ; 39(3): 124-9, 2013 Dec.
Article in English | MEDLINE | ID: mdl-26118160

ABSTRACT

Plants have long been used as herbal medicines in many countries. However, microbial contamination of these medicines may affect human health. Present study was performed to assess the pathogenic proliferation in the locally available commercial herbal oral medicines. The pathogenic load was compared with the microbiological standard given by the British Pharmacopoeia. Out of 85 oral liquid samples, 2 were found to be highly contaminated with a total aerobic bacterial load of 1.24 x 10(5) cfu/ml, 10 samples were contaminated with fungi (1.2 x 10(4)-6.3 x 10(4) cfu/ml). Tests for specific pathogens were carried out. One sample showed contamination by coliforms but none of the samples were contaminated by Salmonella spp. and Shigella spp. Among 40 semisolid samples, one showed to be contaminated with bacteria (1.93 x 10(5) cfu/g) and 5 samples consisted of fungal load ranging between 1.5 x 10(4)-2.2 x 10(4) cfu/g. The presence of bacteria and fungi in these samples thus suggest the fact that aseptic handling is necessary during processing of oral herbal medicines.


Subject(s)
Drug Contamination , Plant Preparations , Bangladesh , Colony Count, Microbial , Cross-Sectional Studies
18.
Poult Sci ; 91(9): 2316-23, 2012 Sep.
Article in English | MEDLINE | ID: mdl-22912469

ABSTRACT

Burgers were prepared using duck surimi-like material (DSLM) with polydextrose added (SL) and DSLM with sucrose-sorbitol added (SS), and the properties of these burgers were compared with those of burgers made of chicken meat (CB) and duck meat (DB). Quality characteristics such as chemical composition, cooking loss, diameter shrinkage, color, and texture were measured. The DB had a lower moisture content (55.58%) and higher fat content (21.44%) and cooking loss (11.01%) compared with other samples, whereas CB, SS, and SL did not differ significantly in moisture (65.21-66.10%) and fat (10.42-11.16%) content or cooking loss (5.32-6.15%). The SS and SL were positioned below CB and above DB in terms of hardness, chewiness, and springiness. Ten trained panelists assessed the burgers using quantitative descriptive analysis. Among the burgers, CB had the greatest brightness of color, hardness, springiness, and chewiness. The SS had greater sweetness than the other burgers. Both SL and SS had significantly less animalic odor, meaty flavor, oiliness, juiciness, and saltiness compared with DB. The physicochemical and sensory characteristics of burgers prepared from DSLM approached those of burgers made of chicken.


Subject(s)
Meat Products/standards , Animals , Cholesterol/chemistry , Consumer Behavior , Cooking , Ducks , Food Handling , Humans , Meat Products/analysis
19.
Poult Sci ; 91(7): 1703-8, 2012 Jul.
Article in English | MEDLINE | ID: mdl-22700518

ABSTRACT

In this study, the effect of the addition of different cryoprotectants on the freeze-thaw stability of duck surimi-like material (DSLM) was tested. A 6% (wt/wt) low-sweetness cryoprotectant (i.e., polydextrose, trehalose, lactitol, or palatinit) was added to a 3-kg portion of DSLM, and the mixture was subjected to freeze-thaw cycles during 4 mo of frozen storage. The DSLM with no cryoprotectant added (control) and with a 6% sucrose-sorbitol blend (high-sweetness cryoprotectant) added also were tested. The polydextrose-added sample had the highest water-holding capacity among the sample types tested (P < 0.05), and it retained its higher value during frozen storage. The protein solubility of the cryoprotectant-added samples decreased significantly (P < 0.05) from 58.99 to 59.60% at initial frozen storage (0 mo) to 48.60 to 54.61% at the end of the experiment (4 mo). The gel breaking force of all samples significantly decreased (P < 0.05) at 1 mo; this breaking force then stabilized after further frozen storage for the cryoprotectant-added samples, whereas it continued to decrease in the control samples. Gel deformation fluctuated during frozen storage and was significantly lower (P < 0.05) at the end of experiment than at the beginning. The presence of cryoprotectants reduced the whiteness of DSLM. Samples containing polydextrose, trehalose, lactitol, and palatinit were able to retain the protein solubility, gel breaking force, and deformation of DSLM better than control samples after 4 mo of frozen storage and exposure to freeze-thaw cycles. The effects of these low-sweetness cryoprotectants are comparable to those of sucrose-sorbitol, thus, these sugars could be used as alternatives in protecting surimi-like materials during frozen storage.


Subject(s)
Cryoprotective Agents/chemistry , Food Handling/methods , Freezing , Meat/analysis , Animals , Ducks
20.
J Food Sci ; 77(1): S91-8, 2012 Jan.
Article in English | MEDLINE | ID: mdl-22260136

ABSTRACT

UNLABELLED: The physicochemical properties and sensory analysis of duck meatballs containing duck meat surimi-like material during frozen storage were evaluated. Properties of meatballs containing duck surimi-like material prepared by acid solubilization (ACDS), alkaline solubilization (ALDS), and conventional processing (CDS) as well as duck mince (as the control, CON) were compared. ACDS had significantly higher (P < 0.05) moisture and protein content and lower fat content compared with CON. The thiobarbituric acid-reactive substances (TBARS) value of all samples increased as the storage time increased up to week 8 (P < 0.05), but thereafter it decreased in most of the samples. ACDS and ALDS had significantly higher TBARS values (P < 0.05), and these values remained higher than those of the other samples throughout the frozen storage period. Addition of surimi-like material to the meatballs had significant effects (P < 0.05) on springiness, gumminess, and chewiness values of all samples. Ingredients and frozen storage affected most sensory attributes in samples significantly (P<0.05). No significant increase in growth of organisms occurred during 12-wk frozen storage The results indicate that acid-alkaline solubilization methods improve both physicochemical and sensory properties of duck meatballs containing duck surimi-like material. Thus, these techniques should be applicable to product development of duck surimi-like material. PRACTICAL APPLICATION: Surimi-like material from duck meat is an alternative source of meat protein to produce ready-to eat or value-added products. Little is known about duck surimi-like material and physicochemical and sensory properties of such products. Therefore, the results of this study are critical for assessing the possibility of duck meat surimi-like material for human food.


Subject(s)
Avian Proteins/chemistry , Frozen Foods/analysis , Meat Products/analysis , Muscle Proteins/chemistry , Animals , Avian Proteins/analysis , Avian Proteins/isolation & purification , Chemical Phenomena , Dietary Fats/analysis , Ducks , Food Handling , Humans , Hydrogen-Ion Concentration , Lipid Peroxidation , Malaysia , Mechanical Phenomena , Muscle Proteins/analysis , Muscle Proteins/isolation & purification , Quality Control , Sensation , Solubility , Time Factors , Water/analysis
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